CIA Lab Researchers, in collaboration with the Department of Pathology at Ohio State University have developed a new method to segment Ki-67 positive nuclei and determine hotspots in the neuroendocrine tumour slide images. The publication, “Perceptual clustering for automatic hotspot detection from Ki-67 stained neuroendocrine tumour images” by Niazi, Yearsley, Zhou, Frankel, and Gurcan will be published in Journal of Microscopy . The methodology can be seen below. This new method attempts to mimic the thought process of a pathologist. It was tested and had an accuracy of 94.60%. This methodology can also be applied to other disease studies in the future.