BMI researcher Metin Gurcan, PhD (Professor, Director of Division
of Clinical and Translational Informatics) in collaboration with Anil Parwani,
MD, PhD, MBA (Vice Chair of Pathology) and Cheryl Lee, MD (Chair of Urology)
have been awarded one of the prestigious OSU Comprehensive Cancer Center
Intramural Research Funding Awards. The research team for the project also
includes Soledad Fernandez, PhD (BMI), Nancy Single (CCC), Khalid Niazi, PhD
(BMI) and Brett Klamer, MS (BMI).
The two-year project, entitled Application of image analysis
tools to accurately stage and risk stratify patients with T1 bladder cancer, will
be primarily funded by Pelotonia dollars. Pelotonia is a three-day bike tour
organized every year in Columbus to raise money for cancer research with one
goal: “End Cancer.” Every rider-raised dollar goes to fund research at The Ohio
State University Comprehensive Cancer Center.
Bladder cancer is an important disease that affects nearly 77,000
people annually. The cancer risk is initially defined by cancer invasion into
the bladder wall. Tumor invasion into the first layer is termed stage T1. It
may be difficult to confirm and sub-stage T1 cancer because of the difficulty
in recognizing all of the anatomic landmarks. This difficulty makes it
challenging for urologists to recommend the right treatment. The proposed study
will develop image analysis tools to stage and risk stratify patients
accurately, which will help urologists make better treatment decisions.
BMI Image Analysis Lab (http://www.bmi.osu.edu/cialab)
will be developing the image analysis algorithms and software for the project.
Founded in 2006 by Dr. Gurcan, the CIALAB’s mission is to develop image
analysis algorithms to improve human health and well-being while training
future research leaders in this field. The qualitative analysis of
histopathological, radiological and dermoscopic images is time-consuming and
subject to inter- and intra-reader variations. These variations may negatively affect
the clinical outcome. The CIALAB has specialized in developing image analysis
systems for computer-assisted interpretation of medical images. The research in
the lab has been supported by the National Cancer Institute, National Institute
of Allergy and Infectious Diseases, National Library of Medicine, American
Cancer Society, Department of Defense, National Rosacea Society, American Acne
and Rosacea Society, American Lung Association, National Football League
Charities, The Children’s Neuroblastoma Cancer Foundation, and the European
Union.
Pelotonia Awardee Dr.
Metin Gurcan riding his bike in Pelotonia 2016 with one goal: “End Cancer.”
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