Clinical Image Analysis

Dr. Sufyan Ababneh has joined the clinical image analysis group as a Biomedical Imaging Specialist. Dr. Ababneh received his BS degree in Electrical and Computer Engineering (ECE) from Jordan University of Science and Technology and his MS Degree in ECE from the University of Alabama in Huntsville. In 2008, he received his PhD degree in ECE from the University of Illinois in Chicago. Prior to that, he was a professional working for several well known companies in the private sector. Prior to joining the Ohio State University, he worked from 2002 to 2006, as a senior developer at Toshiba Medical Research Institute USA Inc and Bio-Imaging Research Inc developing CT-Scan imaging systems. From 1998 to 2002, he served as a senior software engineer at Motorola Inc. From 1997 to 1998, he worked as a Development Consultant for Bio-Imaging Research Inc. From 1995 to 1997, he worked as an Algorithms Developer designing embedded-systems applications at Circuit City. Dr. Ababneh's research int...

CIALAB is pleased to introduce another intern Emine Doganay working through summer’09. Emine Doganay: I am a graduate student in Electrical and Electronics Engineering Department at Fatih University, Istanbul, Turkey. I just started my summer internship in the Clinical Image Analysis Laboratory at The Ohio State University. I am interested in learning about medical image processing and image analysis. As part of my graduate studies, for the last six month, I have been developing automated detection algorithms (computer-aided diagnosis) to recognize hypertensive patients from digital fundus images. For this summer, I have decided to join a group that is working in the medical imaging area. Therefore, I am really happy to be here. I am sincerely grateful to the Ohio State University that has given me this chance and to be a member of excellent group of professionals studying about the medical image processing area. And also I would like to thank to Dr. Gurcan for his help and support.

CIALAB Neuroblastoma research is going to be presented in 2009 MICCAI workshop on Optical Tissue Image Analysis in  Microscopy, Histopathology and Endoscopy (OPTIMHisE) which will be held in Imperial Collage, London, UK on September 24th (http://www.miccai2009.org/). The study titled "A Combined Computerized System for Classifying Digitized Whole-slide Neuroblastoma Histology: Model-based Structural Features," proposes a unified framework that combines the previously developed classification systems for the stromal development and the grade of differentiation and improves the whole-slide classification accuracy of by introducing a set of clinically driven structural features.   Olcay Sertel, Umit V. Catalyurek, Hiroyuki Shimada, and Metin Gurcan, "A Combined Computerized System for Classifying Digitized Whole-slide Neuroblastoma Histology: Model-based Structural Features". Abstract:  Neuroblastoma (NB) is one of the most malignant tumors affecting infants. In clinic...

CIALAB work detailing relationships between the meniscus and cartilage, and their implications in the development and progression of osteoarthritis, has been accepted for presentation at the 2009 OARSI World Congress on Osteoarthritis. The analysis was performed by Jeff Prescott, Furqan Haq PhD, Tom Best MD/PhD, Micheal Pennell PhD, Rebecca Jackson MD, and Metin Gurcan PhD. The full abstract appears below. Purpose : To determine associations between meniscus volume and knee cartilage morphological measurements in subjects with osteoarthritis (OA). Methods : All data was obtained from the Osteoarthritis Initiative’s (OAI) public use dataset (www.oai.ucsf.edu). A sample of progression subjects produced by the OAI was used for the study (Subgroup B, release 0.B.2). Out of the 160 subjects in the sample, two had no discernable meniscus and were excluded, leaving 158 subjects in the analysis. The current study focused on the right knee, as this was the only knee for which cartilage measur...

The Ohio State University Center for Clinical & Translational Science (OSU CCTS) received an NIH grant to create a Summer Research Experience Program (SREP) for high school students and teachers. This funding is part of the American Recovery and Reinvestment Act of 2009 and funds high school students and high school teachers in summer 2009. India Eaton from Eastmoor Academy has joined the CIALAB this summer as an SREP student. India is planning on attending Cleveland State University on the Honors Program scholarship. She will be majoring in mechanical engineering.

CIALAB is pleased to introduce the three interns namely Tong Gan, Rosana Rodriguez Milanes and Michael Priddy working through summer’09. Rosana Rodriguez Milanes - I am a third year undergraduate student in Electronic Engineering from Universidad del Norte, Colombia. My experience as a volunteer foreign student in the Clinical Image Analysis Laboratory has been an edifying, gratifying and enriching. Being able to participate, to learn and to collaborate in the Clinical Image Analysis Laboratory during the past two weeks has allowed me to improve my analytical and interpretative skills in processing histopathological and MRI images. I have been able to learn about segmentation, region growing, splitting and merging algorithms development. I have also had the privilege of knowing and interacting with excellent engineers who have helped me improve my skills as a foreign student. I am grateful for the opportunity that the Ohio State University has given me to collaborate and to learn with...

Jeff Prescott, a student in the CIALAB, has had his work accepted as a regular paper to the 24th International Symposium on Computer and Information Sciences. The work, entitled "Template-Based Level Set Segmentation using Anatomical Information: Application to Quadriceps Muscles in MR Images from the Osteoarthritis Initiative", describes a method for the semi-automated segmentation of quadriceps muscles. Abstract: We present a preliminary evaluation of an automated segmentation method of the quadriceps muscles from MR images of the thigh. The method is being developed to assist research into morphological properties of the quadriceps muscles as biomarkers of osteoarthritis (OA) incidence and progression. Our method uses an anatomically anchored, template-based initialization of the level set-based segmentation approach. A template image is selected using the Kullback-Leibler divergence measure based on the muscle and fat content of the thigh images. Contours of the quadr...